PEER-REVIEWED MANUSCRIPTS (* corresponding author)


2016

  1. 1Drug-Loaded Particles: "Trojan Horses" in the Therapy of Atherosclerosis”, Nikolaos Tsigkas, Srivatsan Kidambi,  Ahmed Tawakol, Yiannis S. Chatzizisis, Atherosclerosis, 2016, doi: 10.1016/j.atherosclerosis.2016.06.050


  1. 2“Astrogliosis in a Dish: Substrate Stiffness Induces Astrogliosis in Primary Rat Astrocytes” Christina Wilson, Stephen Hayward, Srivatsan Kidambi*, RSC Advances, 6, 34447-34457, 2016, doi: 10.1039/C5RA25916A 


                                             


  1. 3Hyaluronic Acid-Conjugated Liposome Nanoparticles for Targeted Delivery to CD44 Overexpressing Glioblastoma Cells” Stephen Hayward, Christina Wilson, Srivatsan Kidambi*, Oncotarget, 2016, doi: 10.18632/oncotarget.8926


                                 


  1. 4“Targeted Delivery of MicroRNA-125a-5p by Engineered Lipid Nanoparticles for the Treatment of HER2 positive Metastatic Breast Cancer”, Stephen Hayward, David Francis, Parviz Kholmatov, Srivatsan Kidambi*, Journal of Biomedical Nanotechnology, 12(3), 554-68, 2016 doi: 10.1166/jbn.2016.2194 

                                             


2015

  1. 5“Substrate Elasticity Regulates Primary Hepatocytes Functions”, Vaishaali Natarajan, Eric Berglund, Dorothy Chen, Srivatsan Kidambi*,  RSC Advances, 5, 80956-80966, 2015, doi: 10.1039/C5RA15208A


                                        


  1. 6“Ionic Driven Embedment of Hyaluronic Acid Coated Liposomes in Polyelectrolyte Multilayer Films for Local Therapeutic Delivery”, Stephen Hayward, David Francis, Matthew Sis, Srivatsan Kidambi*,  Nature Scientific Reports, 5, 14683, 2015, doi: 10.1038/srep14683


                                         


  1. 7“In vitro Co-cultures of Breast Cancer Cells and Stromal Cells to Emulate Tumor Progression and miRNA Profiles of Clinical Conditions”, Amita Daverey, Karleen Brown, Srivatsan Kidambi*, Langmuir, 31(36), 9991-10001, 2015 doi: 10.1021/acs.langmuir.5b02227


                                            


  1. 8“Mitochondrial Dysfunction and Loss of Glutamate Uptake in Primary Astrocytes Exposed to Titanium Dioxide Nanoparticles”, Christina Wilson, Vaishaali Natarajan, Stephen Hayward, Oleh Khalimonchuk, Srivatsan Kidambi*,  Nanoscale, 7(44), 18477-88, 2015 doi: 10.1039/c5nr03646a


                     
     


  1. 9“Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation” Amita Daverey, Allison Drain, Srivatsan Kidambi*,  Nature Scientific Reports,  5, 13744, 2015, doi: 10.1038/srep13744


         
   


  1. 10“Mitochondrial Dysregulation and Loss of Hepatic Functions due to Chronic Exposure to Titanium dioxide Nanoparticles to Primary Hepatocytes”, Vaishaali Natarajan, Christina Wilson, Stephen Hayward, Srivatsan Kidambi*PLOS One, 10(8), e0134541, 2015 doi: 10.1371/journal.pone.0134541 


                                         


  1. 11“Dye-doped silica encapsulated magnetic nano-assemblies for dual optical/MRI imaging and hyperthermia", Sunil Kumar, Dhirendra Bahadur, Amita Daverey, Vahid Khalilzad-Sharghi, Niroj Sahu, Srivatsan Kidambi, Shadi Othman,  RSC Advances, 5, 53180-53188, 2015 doi: 10.1039/C5RA07632C


            


  1. 12“FMR1 Deficiency Alters Self-Renewal, Proliferation, and Pluripotency of Mouse Embryonic Cells”, Shyam Sundhar Bale; Nima Saeidi; Srivatsan Kidambi; Martin Yarmush; Monica Casali, NanoLife, 5(2), 15500, 2015. doi: 10.1142/S1793984415500038


2012

  1. 13“Topography Mediated Regulation of HER-2 Expression in Breast Cancer Cells” Amita Daverey, Austin Mytty, Srivatsan Kidambi *, NanoLife, 2(3), 12410,  2012 doi: 10.1142/S1793984412410097


                     
      
                                                                                              

PRIOR UNL

  1. 14“Propofol induces MAPK/ERK cascade dependant expression of c-Fos and Egr-1 in rat hippocampal slices” Srivatsan Kidambi*, Joel Yarmush, Yevgeny Berdichevsky, Sangeetha Kamath, Wayne Fong, Joseph SchianodiCola, BMC Research Notes, 17(3), 201-206, 2010


  1. 15“Oxygen-Mediated Enhancement of Metabolism, Functional Polarization, Gene Expression an Drug Clearance in Cocultures of Primary Hepatocytes” Srivatsan Kidambi, Eric Novik, Ruby Yarmush, Piyun Chao, Martin Yarmush, Yaakov Nahmias, Proceedings of the National Academy of Science, 106(37), 15714-9, 2009.

  2. 16“Propofol induces a Dose-Dependent Alteration in the Expression of c-Fos and Egr-1 in Neuronal Cells” Srivatsan Kidambi*, Joel Yarmush, Wayne Fong, Sangeetha Kamath, Joseph SchianodiCola, Yaakov Nahmias, NeuroReport, 20(7), 657-662, 2009.

  3. 17“Tunable Resistive m-dPEG Acid Patterns on Polyelectrolyte Multilayers at Physiological Conditions:  Template for Directed Deposition of Biomacromolecules” Srivatsan Kidambi, Christina Chan*, Ilsoon Lee, Langmuir, 24(1),224-30, 2008.

  4. 18“Patterned Co-culture of Neurons and Astrocytes on Polyelectrolyte Multilayer Films for Studying Astrocyte Mediated Oxidative Stress in Neurons” Srivatsan Kidambi, Ilsoon Lee, Christina Chan. Advanced Functional Materials, 18, 294-301, 2008.

  5. 19“Selective Adhesion of Primary Hepatocytes on Polyelectrolyte Multilayers: Template for Patterned Cell Co-culture” Srivatsan Kidambi, Lufang Sheng, Mehmet Toner, Martin Yarmush, Ilsoon Lee, Christina Chan. Macromolecular Biosciences, 7(3), 344-53, 2007.

  6. 20“Cell Adhesion on Polyelectrolyte Multilayer coated PDMS Surfaces with Varying Topographies” Srivatsan Kidambi, Natasha Udpa, Stacey Schroeder, Ilsoon Lee, Christina Chan. Tissue Engineering, 13 (8), 2105-2117, 2007.

  7. 21“Salt tunable m-dPEG Acid Patterns on Polyelectrolyte Multilayer - Templates for Directed Deposition of Macromolecules” Srivatsan Kidambi, Ilsoon Lee, Christina Chan.  Polymer Preprints, 47(1), 41-42, 2006.

  8. 22“Polyelectrolyte Multilayer as Bioactive Surface for Cell Adhesion” Srivatsan Kidambi, Ilsoon Lee, Christina Chan.  Polymer Preprints 46(2), 1271-1272, 2005.

  9. 23"Selective Primary Hepatocyte Adhesion on Polyelectrolyte Multilayer: Template for Patterned Cell Co-culture” Srivatsan Kidambi, Ilsoon Lee, Christina Chan.  AICHE Preprint, 2004.

  10. 24“Engineering Polyelectrolyte Multilayer (PEM) Surfaces to Create Cell Resistant and Adhesive Surfaces” Srivatsan Kidambi, Ilsoon Lee, Christina Chan.  Polymer Preprints 45(1), 88-89, 2004.

  11. 25“Controlling Primary Hepatocyte Adhesion and Spreading on Protein Free Polyelectrolyte Multilayer Films” Srivatsan Kidambi, Ilsoon Lee, Christina Chan. Journal of the American Chemical Society, 126 (50), 16286 -16287, 2004.

  12. 26“Selective Depositions on Polyelectrolyte Multilayers: Self-Assembled Monolayers of m-dPEG Acid as Molecular Templates” Srivatsan Kidambi, Christina Chan, Ilsoon Lee. Journal of the American Chemical Society, 126, 4697-4703, 2004.


Under Review/In Preparation


  1. 27“METH Regulates Astrocytes Function Mediated by Autophagy Pathways”, Christina Wilson, Rick Bevins, Rodrigo Franco Cruz,  Oleh Khalimonchuk, Srivatsan Kidambi*, in preparation


  1. 28“Shape Dependent Toxicity of NanoCeria in Primary Hepatocytes”, Vaishaali Natarajan, Barry Cheung, Srivatsan Kidambi*, in preparation


  1. 29“Surface Stiffness Regulates Receptor Mediated Endocytosis of LNPs” Stephen Hayward, Vaishaali Natarajan, Srivatsan Kidambi*, in preparation


  1. 30“Substrate Elasticity Induces Liver Fibrosis-like Phenotype in Primary LSECs” Vaishaali Natarajan, Carol Casey, Edward Harris, Srivatsan Kidambi*, in preparation


  1. 31“Dysregulation of Mitochondrial Dynamics regulates EMT in Tumor Cells” Amita Daverey, Oleh Khalimonchuk, Srivatsan Kidambi*, in preparation


  1. 32“Tunable Modulation of Breast Cancer Biology due to Dynamic Well-Defined Mechanical Microenvironment” Amita Daverey, Ravi Saraf, Srivatsan Kidambi*, in preparation


  1. 33SECs (Sinusoidal Endothelial Cells), Liver Microenvironment and Fibrosis: Ménage à Trois” Vaishaali Natarajan, Srivatsan Kidambi*, under review


  1. 34Scalable Production of Glioblastoma Cancer Stem Cells in 3 Dimension Thermoreversible Hydrogels", Qiang Li, Haishuang Lin, Ou Wang, Xuefeng Qiu, Srivatsan Kidambi, Loic P Deleyrolle, Brent Reynolds, and Yuguo Lei, under review


PATENTS

  1. 1“Cell Adhesion on Surfaces of Varying Topographies” US 20080241926

  2. 2“Salt and pH tunable Polyelectrolyte Multilayers for uses as bioengineering scaffolds” US 20070224175

  3. 3“Development of Polyelectrolyte Multilayer Coatings for Primary Hepatocyte Cell Culture System” (MSU Invention Number 06-026).

  4. 4“Aptamer Arrays on Polyelectrolyte Multilayer Films” (MSU Invention Number 05-117F).


MEETINGS AND CONFERENCES


Published Abstracts and Proceedings

  1. 1“Salt tunable m-dPEG Acid Patterns on Polyelectrolyte Multilayer - Templates for Directed Deposition of Macromolecules” Srivatsan Kidambi, Ilsoon Lee, Christina Chan. Polymer Preprints, 47(1), 41-42, 2006.

  2. 2“Polyelectrolyte Multilayer as Bioactive Surface for Cell Adhesion” Srivatsan Kidambi, Ilsoon Lee, Christina Chan. Polymer Preprints 46(2), 1271-1272, 2005.

  3. 3Selective Primary Hepatocyte Adhesion on Polyelectrolyte Multilayer: Template for Patterned Cell Co-culture” Srivatsan Kidambi, Ilsoon Lee, Christina Chan. AICHE Preprint, 2004.

  4. 4“Engineering Polyelectrolyte Multilayer (PEM) Surfaces to Create Cell Resistant and Adhesive Surfaces” Srivatsan Kidambi, Ilsoon Lee, Christina Chan. Polymer Preprints 45(1), 88-89, 2004.

Invited Presentations

  1. 1.“Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Department of Materials Science and Engineering, University of Michigan-Ann Arbor, Ann Arbor, MI, Feb, 2016

  2. 2.“Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Nebraska Center for the Prevention of Obesity Diseases Seminar Series, University of Nebraska-Lincoln, Lincoln, NE, Nov, 2015

  3. 3.“Matrix based liver models to investigate the role of microenvironment on liver fibrosis”, International Symposium on the Cells of the Hepatic Sinusoid, Asilomar, CA, Nov, 2015

  4. 4.“Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Fred & Pamela Buffett Cancer Center Grand Rounds, University of Nebraska Medical Center, Omaha, NE, Nov, 2015

  5. 5.“Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Big Ten Seminar Exchange, Department of Biomedical Engineering Northwestern University, Chicago, IL, Nov, 2015

  6. 6.“Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Regenerative Medicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE, Oct, 2015

  7. 7.“WHAT DOES THE STROMAL CELLS SAY (TO THE TUMOR CELLS)? One sound that no one knows….”, Regenerative Medicine, University of Nebraska Medical Center, Omaha, NE, June, 2015

  8. 8.“Engineering Nanostructured Polymer Films for In Vitro Models of Tissue”, Indian Institute of Technology, Madras, India, September, 2014

  9. 9.“Molecular bases of the role of METH-induced inflammation on behavioral abnormalities”, National Institute of Drug Abuse, Bethesda, MD, June, 2014

  10. 10. “Engineering Nanostructured Polymer Films for In Vitro Models of Liver”, University of Nebraska-Lincoln Interdisciplinary Retreat, Lincoln, NE, May, 2014

  11. 11. “Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, University of Nebraska-Lincoln Department of Animal Science, Lincoln, NE, Oct, 2013

  12. 12. “In Vitro Liver Models-Design and Cellular Interaction Studies”, International Symposium on the Cells of the Hepatic Sinusoid, Osaka, Japan, Sep, 2013

  13. 13. “Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Regenerative Medicine, University of Nebraska Medical Center, Omaha, NE, Apr, 2013

  14. 14. “Engineering Nanostructured Polymer Films for In Vitro Models of Living Tissues”, Center for Nanohybrid Functional Materials, University of Nebraska, Lincoln, NE, Mar, 2013

  15. 15. “Propofol induces MAPK/ERK cascade dependant expression of c-Fos and Egr-1 in brain”, Department of Anesthesiology, NY Methodist Hospital, Brooklyn, NY, Aug, 2010.

  16. 16. “Engineering Novel Polyelectrolyte Multilayer Films for Tissue Engineering and Drug Delivery Applications”, Department of Chemical and Biomolecular Engineering, University of Nebraska, Lincoln, NE, June, 2009.

  17. 17. “Engineering Novel Polyelectrolyte Multilayer Films for Tissue Engineering and Drug Delivery Applications”, Department of Biomedical Engineering, University of Akron, Akron, OH, April, 2009.

  18. 18. “Engineering Novel Polyelectrolyte Multilayer Films for Tissue Engineering and Drug Delivery Applications”, Department of Chemical and Biomolecular Engineering, University of Akron, Akron, OH, April, 2009.

  19. 19. “Nanotechnology Approaches for Tissue Engineering and Drug Delivery Applications”, Department of Chemical Engineering, Western Michigan University, Kalamazoo, MI, March, 2009.

  20. 20. “Engineering Novel Polyelectrolyte Multilayer Films for Tissue Engineering and Drug Delivery Applications”, Department of Chemical and Biomolecular Engineering, Nanyang Technological University, Singapore, March, 2009.

  21. 21. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Immune Disease Institute, Harvard Medical School, Boston, MA, November, 2008.

  22. 22. “Salt Tunable m-dPEG Acid Patterns on Polyelectrolyte Multilayer - Templates for Directed Deposition of Macromolecules”, Polymer Science Group, Symyx, Santa Clara, CA, November, 2008.

  23. 23. “Salt tunable m-dPEG Acid Patterns on Polyelectrolyte Multilayer - Templates for Directed Deposition of Macromolecules”, Hitachi Chemical Research Center, Irvine, CA, September, 2008.

  24. 24. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Symyx, Santa Clara, CA, September, 2008. 

  25. 25. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Eli Lilly, Indianapolis, IN, August, 2008.

  26. 26. “Gene Expression Changes in Brain due to Propofol” Department of Anesthesiology, New York Methodist Hospital, Brooklyn, NY, May, 2008.

  27. 27. “Aptamer Incorporated Polyelectrolyte Multilayer Films Targeting Influenza Virus’s Hemagglutinin Binding Region” 234th ACS National Meeting, Boston, MA, August, 2007. (ICI Student Award Finalist in Applied Polymer Science)

  28. 28. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Centre for Engineering in Medicine, Harvard Medical School, MGH, Boston, MA, October, 2006.

  29. 29. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, July, 2006.

  30. 30. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, June, 2006.

  31. 31. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Amgen, San Francisco, CA, March, 2006.

  32. 32. “Engineering Invitro Cellular Microenvironments using Polyelectrolyte Multilayer Films and Microfabrication Techniques to Control Cell Adhesion and for Drug Delivery Applications”, Intel, Portland, OR, November, 2005.

  33. 33. “Synthesis and Characterization of Novel Cellulose Ethers from Environmentally Friendly Starting Products”, Merck, West Point, PA, November, 2002.

 


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